Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data

DNA modification generates unique electric signals in Oxford Nanopore sequencing data but the signals can be complicated to decipher. Here, the authors develop a deep learning framework, DeepMod, to detect DNA base modifications including 5mC and 6mA using Nanopore sequencing data

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Qian Liu, Li Fang, Guoliang Yu, Depeng Wang, Chuan-Le Xiao, Kai Wang
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/2a64c8015b9e434c94ff1733e2720d34
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires