Replication dynamics of recombination-dependent replication forks

Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage sequencing and a Monte Carlo mathematical mod...

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Autores principales:	Karel Naiman, Eduard Campillo-Funollet, Adam T. Watson, Alice Budden, Izumi Miyabe, Antony M. Carr
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2a6dc8952f774e83b7e96e8950dd7e83
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spelling	oai:doaj.org-article:2a6dc8952f774e83b7e96e8950dd7e832021-12-02T14:26:59ZReplication dynamics of recombination-dependent replication forks10.1038/s41467-021-21198-02041-1723https://doaj.org/article/2a6dc8952f774e83b7e96e8950dd7e832021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21198-0https://doaj.org/toc/2041-1723Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage sequencing and a Monte Carlo mathematical model.Karel NaimanEduard Campillo-FunolletAdam T. WatsonAlice BuddenIzumi MiyabeAntony M. CarrNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karel Naiman Eduard Campillo-Funollet Adam T. Watson Alice Budden Izumi Miyabe Antony M. Carr Replication dynamics of recombination-dependent replication forks
description	Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage sequencing and a Monte Carlo mathematical model.
format	article
author	Karel Naiman Eduard Campillo-Funollet Adam T. Watson Alice Budden Izumi Miyabe Antony M. Carr
author_facet	Karel Naiman Eduard Campillo-Funollet Adam T. Watson Alice Budden Izumi Miyabe Antony M. Carr
author_sort	Karel Naiman
title	Replication dynamics of recombination-dependent replication forks
title_short	Replication dynamics of recombination-dependent replication forks
title_full	Replication dynamics of recombination-dependent replication forks
title_fullStr	Replication dynamics of recombination-dependent replication forks
title_full_unstemmed	Replication dynamics of recombination-dependent replication forks
title_sort	replication dynamics of recombination-dependent replication forks
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2a6dc8952f774e83b7e96e8950dd7e83
work_keys_str_mv	AT karelnaiman replicationdynamicsofrecombinationdependentreplicationforks AT eduardcampillofunollet replicationdynamicsofrecombinationdependentreplicationforks AT adamtwatson replicationdynamicsofrecombinationdependentreplicationforks AT alicebudden replicationdynamicsofrecombinationdependentreplicationforks AT izumimiyabe replicationdynamicsofrecombinationdependentreplicationforks AT antonymcarr replicationdynamicsofrecombinationdependentreplicationforks
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Replication dynamics of recombination-dependent replication forks

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