Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live <italic toggle="yes">Escherichia coli</italic>

ABSTRACT In bacteria, elongation factor Tu is a translational cofactor that forms ternary complexes with aminoacyl-tRNA (aa-tRNA) and GTP. Binding of a ternary complex to one of four flexible L7/L12 units on the ribosome tethers a charged tRNA in close proximity to the ribosomal A site. Two sequenti...

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Bibliographic Details
Main Authors: Mainak Mustafi, James C. Weisshaar
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Online Access:https://doaj.org/article/2a7e19598eb5480f80e264f7d712b755
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