Joint analysis of expression levels and histological images identifies genes associated with tissue morphology
Image features from histological slides can be used as informative endophenotypes in association studies for tissue-localized pathologies. Here, the authors develop ImageCCA, a framework for joint analysis of paired gene expression and histology data derived from automatically extracted image featur...
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Autores principales: | Jordan T. Ash, Gregory Darnell, Daniel Munro, Barbara E. Engelhardt |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/2a7e696055bd421b97061786f145137f |
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