Joint analysis of expression levels and histological images identifies genes associated with tissue morphology

Image features from histological slides can be used as informative endophenotypes in association studies for tissue-localized pathologies. Here, the authors develop ImageCCA, a framework for joint analysis of paired gene expression and histology data derived from automatically extracted image featur...

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Autores principales: Jordan T. Ash, Gregory Darnell, Daniel Munro, Barbara E. Engelhardt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2a7e696055bd421b97061786f145137f
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