Glycine, serine and threonine metabolism confounds efficacy of complement-mediated killing
Serum-resistant bacteria can escape complement killing in the bloodstream. Here, using metabolomics and metabolite perturbations, the authors describe an altered metabolic state in serum-resistant Escherichia coli and show that exogenous glycine potentiates elimination of pathogenic bacteria in vivo...
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Autores principales: | Zhi-xue Cheng, Chang Guo, Zhuang-gui Chen, Tian-ci Yang, Jian-ying Zhang, Jie Wang, Jia-xin Zhu, Dan Li, Tian-tuo Zhang, Hui Li, Bo Peng, Xuan-xian Peng |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/2a81a06532b8422685249d3fbec16fbf |
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