Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series

Objective: The endeavor of the study was to analyze the posttreatment (postradioactive iodine therapy [RAI]) conditions of thyrotoxic patients in a tertiary level hospital. Materials and Methods: A retrospective study of 186 patients was conducted from 2012 to 2014 in Institute of Nuclear Medicine a...

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Autores principales:	Md Kayes Mahmud, Shahnaz Jalil, A HM Mahmudur Rahman, Md Mamun-Ur Rashid, Shiny Sultana, Adnan Taher, Lutful Haque, Jannatul Fardous, Kamrun Nahar
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2017
Materias:	Etiology Graves' disease multinodular goiter radioactive iodine therapy thyrotoxicosis Medicine R
Acceso en línea:	https://doaj.org/article/2a8900ed471d49488001418d5e7c715c
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spelling	oai:doaj.org-article:2a8900ed471d49488001418d5e7c715c2021-12-02T01:31:33ZEtiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series2231-0770https://doaj.org/article/2a8900ed471d49488001418d5e7c715c2017-01-01T00:00:00Zhttp://www.avicennajmed.com/article.asp?issn=2231-0770;year=2017;volume=7;issue=3;spage=125;epage=129;aulast=Mahmudhttps://doaj.org/toc/2231-0770Objective: The endeavor of the study was to analyze the posttreatment (postradioactive iodine therapy [RAI]) conditions of thyrotoxic patients in a tertiary level hospital. Materials and Methods: A retrospective study of 186 patients was conducted from 2012 to 2014 in Institute of Nuclear Medicine and Allied Sciences (INMAS), Sylhet MAG Osmani Medical College Campus. Patients' information regarding the etiologies and their disease status after getting RAI therapy was recorded. Results: In this study, 29.57% patients were male and 70.43% were female where the mean ages were 44.57 and 43.46 accordingly. The most vulnerable group was in between 41 and 50 years of age, which is 25.81%. The patients were categorized according to the etiologies as Graves' disease (GD), multinodular goiter (MNG), and single toxic nodule (STN). In primary stage, 60.22% patients had GD, 26.88% had MNG, and 12.90% had STN. After 6 months of RAI therapy, the disease status of 51.61% patients became euthyroid, 19.35% became hypothyroid, and 29.03% remained thyrotoxic. Thus, a second dose of RAI therapy was given to those patients for next 6 months. After 12 months from the beginning of the therapy of each patient, the total recovery was found to be 72.04%. However, though all the GD patients improved to either euthyroid or hypothyroid state after 6 months, on a 12-month observation, 17.86% of them regained the thyrotoxicosis due to discontinuation of the treatment. Conclusion: The findings show an overall significant recovery of thyrotoxic patients taking RAI therapy in INMAS and important points to improve the rate.Md Kayes MahmudShahnaz JalilA HM Mahmudur RahmanMd Mamun-Ur RashidShiny SultanaAdnan TaherLutful HaqueJannatul FardousKamrun NaharThieme Medical and Scientific Publishers Pvt. Ltd.articleEtiologyGraves' diseasemultinodular goiterradioactive iodine therapythyrotoxicosisMedicineRENAvicenna Journal of Medicine, Vol 7, Iss 3, Pp 125-129 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Etiology Graves' disease multinodular goiter radioactive iodine therapy thyrotoxicosis Medicine R
spellingShingle	Etiology Graves' disease multinodular goiter radioactive iodine therapy thyrotoxicosis Medicine R Md Kayes Mahmud Shahnaz Jalil A HM Mahmudur Rahman Md Mamun-Ur Rashid Shiny Sultana Adnan Taher Lutful Haque Jannatul Fardous Kamrun Nahar Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
description	Objective: The endeavor of the study was to analyze the posttreatment (postradioactive iodine therapy [RAI]) conditions of thyrotoxic patients in a tertiary level hospital. Materials and Methods: A retrospective study of 186 patients was conducted from 2012 to 2014 in Institute of Nuclear Medicine and Allied Sciences (INMAS), Sylhet MAG Osmani Medical College Campus. Patients' information regarding the etiologies and their disease status after getting RAI therapy was recorded. Results: In this study, 29.57% patients were male and 70.43% were female where the mean ages were 44.57 and 43.46 accordingly. The most vulnerable group was in between 41 and 50 years of age, which is 25.81%. The patients were categorized according to the etiologies as Graves' disease (GD), multinodular goiter (MNG), and single toxic nodule (STN). In primary stage, 60.22% patients had GD, 26.88% had MNG, and 12.90% had STN. After 6 months of RAI therapy, the disease status of 51.61% patients became euthyroid, 19.35% became hypothyroid, and 29.03% remained thyrotoxic. Thus, a second dose of RAI therapy was given to those patients for next 6 months. After 12 months from the beginning of the therapy of each patient, the total recovery was found to be 72.04%. However, though all the GD patients improved to either euthyroid or hypothyroid state after 6 months, on a 12-month observation, 17.86% of them regained the thyrotoxicosis due to discontinuation of the treatment. Conclusion: The findings show an overall significant recovery of thyrotoxic patients taking RAI therapy in INMAS and important points to improve the rate.
format	article
author	Md Kayes Mahmud Shahnaz Jalil A HM Mahmudur Rahman Md Mamun-Ur Rashid Shiny Sultana Adnan Taher Lutful Haque Jannatul Fardous Kamrun Nahar
author_facet	Md Kayes Mahmud Shahnaz Jalil A HM Mahmudur Rahman Md Mamun-Ur Rashid Shiny Sultana Adnan Taher Lutful Haque Jannatul Fardous Kamrun Nahar
author_sort	Md Kayes Mahmud
title	Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
title_short	Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
title_full	Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
title_fullStr	Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
title_full_unstemmed	Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series
title_sort	etiologies and posttreatment conditions of thyrotoxic patients in sylhet division, bangladesh: a clinical series
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2017
url	https://doaj.org/article/2a8900ed471d49488001418d5e7c715c
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Etiologies and posttreatment conditions of thyrotoxic patients in Sylhet division, Bangladesh: A clinical series

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