Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

Abstract We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Als...

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Autores principales: Kristi Krüger, Elisabeth Wik, Gøril Knutsvik, Hawa Nalwoga, Tor A. Klingen, Jarle B. Arnes, Ying Chen, Monica Mannelqvist, Konstantina Dimitrakopoulou, Ingunn M. Stefansson, Even Birkeland, Turid Aas, Nicholas P. Tobin, Inge Jonassen, Jonas Bergh, William D. Foulkes, Lars A. Akslen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2a8a20fe1d2e4fe7af3fd1ff76db984e
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