Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

Abstract We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Als...

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Main Authors: Kristi Krüger, Elisabeth Wik, Gøril Knutsvik, Hawa Nalwoga, Tor A. Klingen, Jarle B. Arnes, Ying Chen, Monica Mannelqvist, Konstantina Dimitrakopoulou, Ingunn M. Stefansson, Even Birkeland, Turid Aas, Nicholas P. Tobin, Inge Jonassen, Jonas Bergh, William D. Foulkes, Lars A. Akslen
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/2a8a20fe1d2e4fe7af3fd1ff76db984e
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