Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

Abstract The density and distribution pattern of epitopes at the surface of pathogens have a profound impact on immune responses. Although multiple lines of evidence highlight the significance of antigen surface density for antibody binding, a quantitative description of its effect on recognition me...

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Autores principales: Maya Hadzhieva, Anastas D. Pashov, Srinivas Kaveri, Sébastien Lacroix-Desmazes, Hugo Mouquet, Jordan D. Dimitrov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2a9f6eab595e44edb829b92bb61362e7
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