Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia

Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia

Abstract Background Administration of propofol, an intravenous anesthetic with antioxidant property, immediately at the onset of post-ischemic reperfusion (propofol postconditioning, P-PostC) has been shown to confer cardioprotection against ischemia–reperfusion injury, while the underlying mechanis...

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Bibliographic Details
Main Authors: Rong-Hui Han, He-Meng Huang, Hong Han, Hao Chen, Fei Zeng, Xiang Xie, Dan-Yong Liu, Yin Cai, Liang-Qing Zhang, Xin Liu, Zheng-Yuan Xia, Jing Tang
Format: article
Language:EN
Published: BMC 2021
Subjects:
H/R injury
Hyperglycemia
P-PostC
Apoptosis
Autophagy
FoxO
Medicine (General)
R5-920
Military Science
U
Online Access:https://doaj.org/article/2aaabbf8f80f47518055e4944a2e55db
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https://doaj.org/article/2aaabbf8f80f47518055e4944a2e55db

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