Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli

Here, we show that RNase E, RhlB, and PNPase act together as components of the multienzyme RNA degradosome in polyribosome-dependent clustering to form puncta on the inner cytoplasmic membrane. Our results support the hypothesis that RNA degradosome puncta are sites of mRNA degradation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Lina Hamouche, Leonora Poljak, Agamemnon J. Carpousis
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/2ab420d966554c73892b417aa365d4ca
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2ab420d966554c73892b417aa365d4ca
record_format	dspace
spelling	oai:doaj.org-article:2ab420d966554c73892b417aa365d4ca2021-11-03T21:52:35ZPolyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli2150-751110.1128/mBio.01932-21https://doaj.org/article/2ab420d966554c73892b417aa365d4ca2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01932-21https://doaj.org/toc/2150-7511 Here, we show that RNase E, RhlB, and PNPase act together as components of the multienzyme RNA degradosome in polyribosome-dependent clustering to form puncta on the inner cytoplasmic membrane. Our results support the hypothesis that RNA degradosome puncta are sites of mRNA degradation.Lina HamoucheLeonora PoljakAgamemnon J. CarpousisAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Lina Hamouche Leonora Poljak Agamemnon J. Carpousis Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
description	Here, we show that RNase E, RhlB, and PNPase act together as components of the multienzyme RNA degradosome in polyribosome-dependent clustering to form puncta on the inner cytoplasmic membrane. Our results support the hypothesis that RNA degradosome puncta are sites of mRNA degradation.
format	article
author	Lina Hamouche Leonora Poljak Agamemnon J. Carpousis
author_facet	Lina Hamouche Leonora Poljak Agamemnon J. Carpousis
author_sort	Lina Hamouche
title	Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
title_short	Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
title_full	Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
title_fullStr	Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
title_full_unstemmed	Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli
title_sort	polyribosome-dependent clustering of membrane-anchored rna degradosomes to form sites of mrna degradation in escherichia coli
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/2ab420d966554c73892b417aa365d4ca
work_keys_str_mv	AT linahamouche polyribosomedependentclusteringofmembraneanchoredrnadegradosomestoformsitesofmrnadegradationinescherichiacoli AT leonorapoljak polyribosomedependentclusteringofmembraneanchoredrnadegradosomestoformsitesofmrnadegradationinescherichiacoli AT agamemnonjcarpousis polyribosomedependentclusteringofmembraneanchoredrnadegradosomestoformsitesofmrnadegradationinescherichiacoli
_version_	1718445385333080064

Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli

Ejemplares similares