Machine learning modelling of blood lipid biomarkers in familial hypercholesterolaemia versus polygenic/environmental dyslipidaemia

Abstract Familial hypercholesterolaemia increases circulating LDL-C levels and leads to premature cardiovascular disease when undiagnosed or untreated. Current guidelines support genetic testing in patients complying with clinical diagnostic criteria and cascade screening of their family members. Ho...

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Autores principales: Marta Correia, Eva Kagenaar, Daniël Bernardus van Schalkwijk, Mafalda Bourbon, Margarida Gama-Carvalho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2ab9736d59e0404a97e8cefb7a0a19cd
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