Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling

ABSTRACT Bats are reservoirs for many RNA viruses that are highly pathogenic in humans yet relatively apathogenic in the natural host. It has been suggested that differences in innate immunity are responsible. The antiviral OAS-RNase L pathway is well characterized in humans, but there is little kno...

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Auteurs principaux: Yize Li, Beihua Dong, Zuzhang Wei, Robert H. Silverman, Susan R. Weiss
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
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Accès en ligne:https://doaj.org/article/2abfddbc4d7a4d08a4995b7c0658a0d9
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