Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors

Childhood neuroblastoma can be separated into high and low risk groups, with prognosis depending on age at diagnosis. Here, the authors show that low and high risk neuroblastoma tumours are composed of different cell types with different malignancy potential.

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Autores principales:	O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. C. Juhlin, P. Kogner, S. Schlisio
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2ac0672b775e4f4eafbfba1aed0015e6
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spelling	oai:doaj.org-article:2ac0672b775e4f4eafbfba1aed0015e62021-12-02T17:42:11ZSingle-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors10.1038/s41467-021-24870-72041-1723https://doaj.org/article/2ac0672b775e4f4eafbfba1aed0015e62021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24870-7https://doaj.org/toc/2041-1723Childhood neuroblastoma can be separated into high and low risk groups, with prognosis depending on age at diagnosis. Here, the authors show that low and high risk neuroblastoma tumours are composed of different cell types with different malignancy potential.O. C. Bedoya-ReinaW. LiM. ArceoM. PlescherP. BullovaH. PuiM. KauckaP. KharchenkoT. MartinssonJ. HolmbergI. AdameykoQ. DengC. LarssonC. C. JuhlinP. KognerS. SchlisioNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q O. C. Bedoya-Reina W. Li M. Arceo M. Plescher P. Bullova H. Pui M. Kaucka P. Kharchenko T. Martinsson J. Holmberg I. Adameyko Q. Deng C. Larsson C. C. Juhlin P. Kogner S. Schlisio Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
description	Childhood neuroblastoma can be separated into high and low risk groups, with prognosis depending on age at diagnosis. Here, the authors show that low and high risk neuroblastoma tumours are composed of different cell types with different malignancy potential.
format	article
author	O. C. Bedoya-Reina W. Li M. Arceo M. Plescher P. Bullova H. Pui M. Kaucka P. Kharchenko T. Martinsson J. Holmberg I. Adameyko Q. Deng C. Larsson C. C. Juhlin P. Kogner S. Schlisio
author_facet	O. C. Bedoya-Reina W. Li M. Arceo M. Plescher P. Bullova H. Pui M. Kaucka P. Kharchenko T. Martinsson J. Holmberg I. Adameyko Q. Deng C. Larsson C. C. Juhlin P. Kogner S. Schlisio
author_sort	O. C. Bedoya-Reina
title	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
title_short	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
title_full	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
title_fullStr	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
title_full_unstemmed	Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
title_sort	single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2ac0672b775e4f4eafbfba1aed0015e6
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Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors

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