The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

Large protein complexes and ribonucleoprotein particles (RNPs) such as pre-ribosomes are transported from the nucleus to the cytoplasm through the nuclear pore complex (NPC). Here the authors use ultrafast freezing and electron tomography to catch snapshots of native RNPs crossing the NPC and estima...

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Auteurs principaux:	Franck Delavoie, Vanessa Soldan, Dana Rinaldi, Jean-Yves Dauxois, Pierre-Emmanuel Gleizes
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/2ac35b113c5741eebe5bb4209d6e5eea
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spelling	oai:doaj.org-article:2ac35b113c5741eebe5bb4209d6e5eea2021-12-02T14:39:38ZThe path of pre-ribosomes through the nuclear pore complex revealed by electron tomography10.1038/s41467-019-08342-72041-1723https://doaj.org/article/2ac35b113c5741eebe5bb4209d6e5eea2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08342-7https://doaj.org/toc/2041-1723Large protein complexes and ribonucleoprotein particles (RNPs) such as pre-ribosomes are transported from the nucleus to the cytoplasm through the nuclear pore complex (NPC). Here the authors use ultrafast freezing and electron tomography to catch snapshots of native RNPs crossing the NPC and estimate their transit time using a probabilistic model.Franck DelavoieVanessa SoldanDana RinaldiJean-Yves DauxoisPierre-Emmanuel GleizesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Franck Delavoie Vanessa Soldan Dana Rinaldi Jean-Yves Dauxois Pierre-Emmanuel Gleizes The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
description	Large protein complexes and ribonucleoprotein particles (RNPs) such as pre-ribosomes are transported from the nucleus to the cytoplasm through the nuclear pore complex (NPC). Here the authors use ultrafast freezing and electron tomography to catch snapshots of native RNPs crossing the NPC and estimate their transit time using a probabilistic model.
format	article
author	Franck Delavoie Vanessa Soldan Dana Rinaldi Jean-Yves Dauxois Pierre-Emmanuel Gleizes
author_facet	Franck Delavoie Vanessa Soldan Dana Rinaldi Jean-Yves Dauxois Pierre-Emmanuel Gleizes
author_sort	Franck Delavoie
title	The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
title_short	The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
title_full	The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
title_fullStr	The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
title_full_unstemmed	The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
title_sort	path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2ac35b113c5741eebe5bb4209d6e5eea
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The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

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