Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei.

Trypanosoma brucei is a master of antigenic variation and immune response evasion. Utilizing a genomic repertoire of more than 1000 Variant Surface Glycoprotein-encoding genes (VSGs), T. brucei can change its protein coat by "switching" from the expression of one VSG to another. Each activ...

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Autores principales: Galadriel A Hovel-Miner, Catharine E Boothroyd, Monica Mugnier, Oliver Dreesen, George A M Cross, F Nina Papavasiliou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/2ac56ca86ee74f68815bab01b552c435
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