Cryo-EM structure of the respiratory syncytial virus RNA polymerase

Cryo-EM structure of the respiratory syncytial virus RNA polymerase

Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.

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Detalles Bibliográficos
Autores principales: Dongdong Cao, Yunrong Gao, Claire Roesler, Samantha Rice, Paul D’Cunha, Lisa Zhuang, Julia Slack, Mason Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, Bo Liang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/2acb3735a4264456be4a72bc93dc7d0d
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Descripción
Sumario:Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.

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