Cryo-EM structure of the respiratory syncytial virus RNA polymerase

Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.

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Autores principales:	Dongdong Cao, Yunrong Gao, Claire Roesler, Samantha Rice, Paul D’Cunha, Lisa Zhuang, Julia Slack, Mason Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, Bo Liang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2acb3735a4264456be4a72bc93dc7d0d
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spelling	oai:doaj.org-article:2acb3735a4264456be4a72bc93dc7d0d2021-12-02T17:32:14ZCryo-EM structure of the respiratory syncytial virus RNA polymerase10.1038/s41467-019-14246-32041-1723https://doaj.org/article/2acb3735a4264456be4a72bc93dc7d0d2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14246-3https://doaj.org/toc/2041-1723Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.Dongdong CaoYunrong GaoClaire RoeslerSamantha RicePaul D’CunhaLisa ZhuangJulia SlackMason DomkeAnna AntonovaSarah RomanelliShayon KeatingGabriela ForeroPuneet JunejaBo LiangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dongdong Cao Yunrong Gao Claire Roesler Samantha Rice Paul D’Cunha Lisa Zhuang Julia Slack Mason Domke Anna Antonova Sarah Romanelli Shayon Keating Gabriela Forero Puneet Juneja Bo Liang Cryo-EM structure of the respiratory syncytial virus RNA polymerase
description	Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.
format	article
author	Dongdong Cao Yunrong Gao Claire Roesler Samantha Rice Paul D’Cunha Lisa Zhuang Julia Slack Mason Domke Anna Antonova Sarah Romanelli Shayon Keating Gabriela Forero Puneet Juneja Bo Liang
author_facet	Dongdong Cao Yunrong Gao Claire Roesler Samantha Rice Paul D’Cunha Lisa Zhuang Julia Slack Mason Domke Anna Antonova Sarah Romanelli Shayon Keating Gabriela Forero Puneet Juneja Bo Liang
author_sort	Dongdong Cao
title	Cryo-EM structure of the respiratory syncytial virus RNA polymerase
title_short	Cryo-EM structure of the respiratory syncytial virus RNA polymerase
title_full	Cryo-EM structure of the respiratory syncytial virus RNA polymerase
title_fullStr	Cryo-EM structure of the respiratory syncytial virus RNA polymerase
title_full_unstemmed	Cryo-EM structure of the respiratory syncytial virus RNA polymerase
title_sort	cryo-em structure of the respiratory syncytial virus rna polymerase
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2acb3735a4264456be4a72bc93dc7d0d
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Cryo-EM structure of the respiratory syncytial virus RNA polymerase

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