Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Long non-coding RNAs are implicated in multiple aspects of tumourigenesis. Here, the authors generate a landscape of these macromolecules in a wide array of cancer types and examine which RNAs are transcriptionally altered in relation to somatic driver mutations in established coding cancer genes.

Guardado en:

Detalles Bibliográficos
Autores principales:	Arghavan Ashouri, Volkan I. Sayin, Jimmy Van den Eynden, Simranjit X. Singh, Thales Papagiannakopoulos, Erik Larsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2ad05e572f2746ae947259830015e60a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2ad05e572f2746ae947259830015e60a
record_format	dspace
spelling	oai:doaj.org-article:2ad05e572f2746ae947259830015e60a2021-12-02T16:49:42ZPan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events10.1038/ncomms131972041-1723https://doaj.org/article/2ad05e572f2746ae947259830015e60a2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13197https://doaj.org/toc/2041-1723Long non-coding RNAs are implicated in multiple aspects of tumourigenesis. Here, the authors generate a landscape of these macromolecules in a wide array of cancer types and examine which RNAs are transcriptionally altered in relation to somatic driver mutations in established coding cancer genes.Arghavan AshouriVolkan I. SayinJimmy Van den EyndenSimranjit X. SinghThales PapagiannakopoulosErik LarssonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arghavan Ashouri Volkan I. Sayin Jimmy Van den Eynden Simranjit X. Singh Thales Papagiannakopoulos Erik Larsson Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
description	Long non-coding RNAs are implicated in multiple aspects of tumourigenesis. Here, the authors generate a landscape of these macromolecules in a wide array of cancer types and examine which RNAs are transcriptionally altered in relation to somatic driver mutations in established coding cancer genes.
format	article
author	Arghavan Ashouri Volkan I. Sayin Jimmy Van den Eynden Simranjit X. Singh Thales Papagiannakopoulos Erik Larsson
author_facet	Arghavan Ashouri Volkan I. Sayin Jimmy Van den Eynden Simranjit X. Singh Thales Papagiannakopoulos Erik Larsson
author_sort	Arghavan Ashouri
title	Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
title_short	Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
title_full	Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
title_fullStr	Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
title_full_unstemmed	Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
title_sort	pan-cancer transcriptomic analysis associates long non-coding rnas with key mutational driver events
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2ad05e572f2746ae947259830015e60a
work_keys_str_mv	AT arghavanashouri pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents AT volkanisayin pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents AT jimmyvandeneynden pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents AT simranjitxsingh pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents AT thalespapagiannakopoulos pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents AT eriklarsson pancancertranscriptomicanalysisassociateslongnoncodingrnaswithkeymutationaldriverevents
_version_	1718383205113921536

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Ejemplares similares