Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Long non-coding RNAs are implicated in multiple aspects of tumourigenesis. Here, the authors generate a landscape of these macromolecules in a wide array of cancer types and examine which RNAs are transcriptionally altered in relation to somatic driver mutations in established coding cancer genes.

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Autores principales: Arghavan Ashouri, Volkan I. Sayin, Jimmy Van den Eynden, Simranjit X. Singh, Thales Papagiannakopoulos, Erik Larsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/2ad05e572f2746ae947259830015e60a
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