Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity

The functions of microbial hydrogen peroxide (H2O2) in host-pathogen interactions are unclear. Here, Erttmann and Gekara show that H2O2 released by Streptococcus pneumoniae inhibits inflammasomes, and thereby contributes to the pathogen’s ability to colonize the host.

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Detalles Bibliográficos
Autores principales:	Saskia F. Erttmann, Nelson O. Gekara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2ad1f8e2c0c84d7d9d050f990faeb40e
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spelling	oai:doaj.org-article:2ad1f8e2c0c84d7d9d050f990faeb40e2021-12-02T16:58:16ZHydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity10.1038/s41467-019-11169-x2041-1723https://doaj.org/article/2ad1f8e2c0c84d7d9d050f990faeb40e2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11169-xhttps://doaj.org/toc/2041-1723The functions of microbial hydrogen peroxide (H2O2) in host-pathogen interactions are unclear. Here, Erttmann and Gekara show that H2O2 released by Streptococcus pneumoniae inhibits inflammasomes, and thereby contributes to the pathogen’s ability to colonize the host.Saskia F. ErttmannNelson O. GekaraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Saskia F. Erttmann Nelson O. Gekara Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
description	The functions of microbial hydrogen peroxide (H2O2) in host-pathogen interactions are unclear. Here, Erttmann and Gekara show that H2O2 released by Streptococcus pneumoniae inhibits inflammasomes, and thereby contributes to the pathogen’s ability to colonize the host.
format	article
author	Saskia F. Erttmann Nelson O. Gekara
author_facet	Saskia F. Erttmann Nelson O. Gekara
author_sort	Saskia F. Erttmann
title	Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
title_short	Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
title_full	Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
title_fullStr	Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
title_full_unstemmed	Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
title_sort	hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2ad1f8e2c0c84d7d9d050f990faeb40e
work_keys_str_mv	AT saskiaferttmann hydrogenperoxidereleasebybacteriasuppressesinflammasomedependentinnateimmunity AT nelsonogekara hydrogenperoxidereleasebybacteriasuppressesinflammasomedependentinnateimmunity
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Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity

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