The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Differences in thalamic structure have been observed in several psychiatric disorders, but the genetic overlap has not been explored. Here, the authors perform a genome-wide association study on thalamic nuclei volume and find genetic loci in common between thalamic volumes and brain disorders.
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Nature Portfolio
2021
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oai:doaj.org-article:2ad2fe7c6a8d4d90bd1505975e08bea32021-12-02T16:51:29ZThe genetic architecture of the human thalamus and its overlap with ten common brain disorders10.1038/s41467-021-23175-z2041-1723https://doaj.org/article/2ad2fe7c6a8d4d90bd1505975e08bea32021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23175-zhttps://doaj.org/toc/2041-1723Differences in thalamic structure have been observed in several psychiatric disorders, but the genetic overlap has not been explored. Here, the authors perform a genome-wide association study on thalamic nuclei volume and find genetic loci in common between thalamic volumes and brain disorders.Torbjørn ElvsåshagenAlexey ShadrinOleksandr FreiDennis van der MeerShahram BahramiVinod Jangir KumarOlav SmelandLars T. WestlyeOle A. AndreassenTobias KaufmannNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
| spellingShingle |
Science Q Torbjørn Elvsåshagen Alexey Shadrin Oleksandr Frei Dennis van der Meer Shahram Bahrami Vinod Jangir Kumar Olav Smeland Lars T. Westlye Ole A. Andreassen Tobias Kaufmann The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| description |
Differences in thalamic structure have been observed in several psychiatric disorders, but the genetic overlap has not been explored. Here, the authors perform a genome-wide association study on thalamic nuclei volume and find genetic loci in common between thalamic volumes and brain disorders. |
| format |
article |
| author |
Torbjørn Elvsåshagen Alexey Shadrin Oleksandr Frei Dennis van der Meer Shahram Bahrami Vinod Jangir Kumar Olav Smeland Lars T. Westlye Ole A. Andreassen Tobias Kaufmann |
| author_facet |
Torbjørn Elvsåshagen Alexey Shadrin Oleksandr Frei Dennis van der Meer Shahram Bahrami Vinod Jangir Kumar Olav Smeland Lars T. Westlye Ole A. Andreassen Tobias Kaufmann |
| author_sort |
Torbjørn Elvsåshagen |
| title |
The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| title_short |
The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| title_full |
The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| title_fullStr |
The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| title_full_unstemmed |
The genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| title_sort |
genetic architecture of the human thalamus and its overlap with ten common brain disorders |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/2ad2fe7c6a8d4d90bd1505975e08bea3 |
| work_keys_str_mv |
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