SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia

SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia

B cells play a central role in the pathogenesis of immune thrombocytopenia (ITP) by participating in humoral immunity. Meanwhile, regulatory B cells (Bregs), one subset of B cells, express negative regulatory effect on ITP. Mesenchymal stem cells (MSCs) have been demonstrated in the ability to induc...

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Autores principales: Zhe Chen, Shufen Zhou, Jianyun Li, Hui Li, Can Huang, Qin Guo, Tiantian Zhang, Bingya Yang, Chuanqing Tu, Chengshan Guo
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
Materias:
Internal medicine
RC31-1245
Acceso en línea:https://doaj.org/article/2ad7dab7ede940b69ac3739e49db3f73
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