Clinical Sports Medicine

Purpose: The menopausal transition is a critical period in womens lives. The central aim of the present study was to evaluate the effect of a multimodal exercise protocol on the cardiometabolic risk factor potentially related to menopausal transition in early postmenopausal women. Methods: Fifty-fou...

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Autores principales: Hettchen M, von Stengel S, Kohl M, Murphy MH, Shojaa M, Ghasemikaram M, Bragonzoni L, Benvenuti F, Ripamonti C, Benedetti G, Julin M, Risto T, Kemmler W
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EN
Publicado: Dynamic Media Sales Verlag 2021
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Acceso en línea:https://doaj.org/article/2ae2a50e458446528abeb2b8a6698a2f
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spelling oai:doaj.org-article:2ae2a50e458446528abeb2b8a6698a2f2021-11-16T19:01:40ZClinical Sports Medicine0344-59252510-526410.5960/dzsm.2020.449https://doaj.org/article/2ae2a50e458446528abeb2b8a6698a2f2021-02-01T00:00:00Zhttps://www.germanjournalsportsmedicine.com/archiv/archive-2021/issue-1/effects-of-high-intensity-aerobic-exercise-and-resistance-training-on-cardiometabolic-risk-in-early-postmenopausal-women/https://doaj.org/toc/0344-5925https://doaj.org/toc/2510-5264Purpose: The menopausal transition is a critical period in womens lives. The central aim of the present study was to evaluate the effect of a multimodal exercise protocol on the cardiometabolic risk factor potentially related to menopausal transition in early postmenopausal women. Methods: Fifty-four (54) early-postmenopausal women (54.01.8 years) were randomly assigned to two groups: (1) exercise group (EG: n=27) which conducted a high intensity aerobic and resistance training three times/week and (2) active control group (CG: n=27) exercising once a week with low exercise intensity. Besides bone density, the main variable of this project, the outcome variable in this thesis was also cardiometabolic risk, as summarized by the Metabolic Syndrome (MetS) Z-Score. We applied Intention-to-Treat (ITT) and Per Protocol Analyses (PPA) with multiple imputation and used standardized mean differences to illustrate the effects.Results: After 16 weeks of exercise two participants (EG: n=1; CG: n=1) were lost to follow-up. Effects for the MetS Z-Score were moderate (EG: -0.361.36 vs. CG: 0.512.28; SMD: 0.47, 95% CI: -0.08 to 1.03), albeit borderline non-significant (ITT: p=.089; PPA: p=.060). Conclusion: The present multimodal exercise protocol just failed to affect the MetS Z-Score and its underlying cardiometabolic risk factors. Whether this result can be generalized to the entire cohort of early-postmenopausal women or whether it has to be attributed to the only moderately high exercise intensity during the early weeks of the intervention along with a relatively short intervention period remains to be evaluated.Key Words: Metabolic Syndrome, MetS Z-Score, Menopausal TransitionHettchen Mvon Stengel SKohl MMurphy MHShojaa MGhasemikaram MBragonzoni LBenvenuti FRipamonti CBenedetti GJulin MRisto TKemmler WDynamic Media Sales VerlagarticleSports medicineRC1200-1245DEENDeutsche Zeitschrift für Sportmedizin, Vol 72, Iss 1 (2021)
institution DOAJ
collection DOAJ
language DE
EN
topic Sports medicine
RC1200-1245
spellingShingle Sports medicine
RC1200-1245
Hettchen M
von Stengel S
Kohl M
Murphy MH
Shojaa M
Ghasemikaram M
Bragonzoni L
Benvenuti F
Ripamonti C
Benedetti G
Julin M
Risto T
Kemmler W
Clinical Sports Medicine
description Purpose: The menopausal transition is a critical period in womens lives. The central aim of the present study was to evaluate the effect of a multimodal exercise protocol on the cardiometabolic risk factor potentially related to menopausal transition in early postmenopausal women. Methods: Fifty-four (54) early-postmenopausal women (54.01.8 years) were randomly assigned to two groups: (1) exercise group (EG: n=27) which conducted a high intensity aerobic and resistance training three times/week and (2) active control group (CG: n=27) exercising once a week with low exercise intensity. Besides bone density, the main variable of this project, the outcome variable in this thesis was also cardiometabolic risk, as summarized by the Metabolic Syndrome (MetS) Z-Score. We applied Intention-to-Treat (ITT) and Per Protocol Analyses (PPA) with multiple imputation and used standardized mean differences to illustrate the effects.Results: After 16 weeks of exercise two participants (EG: n=1; CG: n=1) were lost to follow-up. Effects for the MetS Z-Score were moderate (EG: -0.361.36 vs. CG: 0.512.28; SMD: 0.47, 95% CI: -0.08 to 1.03), albeit borderline non-significant (ITT: p=.089; PPA: p=.060). Conclusion: The present multimodal exercise protocol just failed to affect the MetS Z-Score and its underlying cardiometabolic risk factors. Whether this result can be generalized to the entire cohort of early-postmenopausal women or whether it has to be attributed to the only moderately high exercise intensity during the early weeks of the intervention along with a relatively short intervention period remains to be evaluated.Key Words: Metabolic Syndrome, MetS Z-Score, Menopausal Transition
format article
author Hettchen M
von Stengel S
Kohl M
Murphy MH
Shojaa M
Ghasemikaram M
Bragonzoni L
Benvenuti F
Ripamonti C
Benedetti G
Julin M
Risto T
Kemmler W
author_facet Hettchen M
von Stengel S
Kohl M
Murphy MH
Shojaa M
Ghasemikaram M
Bragonzoni L
Benvenuti F
Ripamonti C
Benedetti G
Julin M
Risto T
Kemmler W
author_sort Hettchen M
title Clinical Sports Medicine
title_short Clinical Sports Medicine
title_full Clinical Sports Medicine
title_fullStr Clinical Sports Medicine
title_full_unstemmed Clinical Sports Medicine
title_sort clinical sports medicine
publisher Dynamic Media Sales Verlag
publishDate 2021
url https://doaj.org/article/2ae2a50e458446528abeb2b8a6698a2f
work_keys_str_mv AT hettchenm clinicalsportsmedicine
AT vonstengels clinicalsportsmedicine
AT kohlm clinicalsportsmedicine
AT murphymh clinicalsportsmedicine
AT shojaam clinicalsportsmedicine
AT ghasemikaramm clinicalsportsmedicine
AT bragonzonil clinicalsportsmedicine
AT benvenutif clinicalsportsmedicine
AT ripamontic clinicalsportsmedicine
AT benedettig clinicalsportsmedicine
AT julinm clinicalsportsmedicine
AT ristot clinicalsportsmedicine
AT kemmlerw clinicalsportsmedicine
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