MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene.

MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene.

<h4>Background</h4>Estrogen receptor α (ERα) has been shown to protect against atherosclerosis. Methylation of the ERα gene can reduce ERα expression leading to a higher risk for cardiovascular disease. Recently, microRNAs have been found to regulate DNA methyltransferases (DNMTs) and th...

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Autores principales: Yung-Song Wang, Wen-Wen Chou, Ku-Chung Chen, Hsin-Yun Cheng, Ruey-Tay Lin, Suh-Hang Hank Juo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2ae2aa9a21a84628876f07b4f3e560ad
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