The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

Abstract Cisplatin, a potent anticancer drug, is usually causing nephrotoxicity; limiting its therapeutic application and efficiency. Maltol may be used to prevent such toxic effect. The aim of this study was to investigate the underlying protective mechanisms of maltol on nephrotoxicity by cisplati...

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Bibliographic Details
Main Authors: Xiao-jie Mi, Jin-gang Hou, Zi Wang, Ye Han, Shen Ren, Jun-nan Hu, Chen Chen, Wei Li
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/2ae4566f8538477387f5275278a4aaad
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