Retinoblastoma from human stem cell-derived retinal organoids

Código QR

Retinoblastoma from human stem cell-derived retinal organoids

Retinoblastoma is a heritable pediatric cancer driven by mutations in RB1. Here, the authors demonstrate the first patient derived model of retinoblastoma using iPSCs from patients with germline mutations in RB1.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jackie L. Norrie, Anjana Nityanandam, Karen Lai, Xiang Chen, Matthew Wilson, Elizabeth Stewart, Lyra Griffiths, Hongjian Jin, Gang Wu, Brent Orr, Quynh Tran, Sariah Allen, Colleen Reilly, Xin Zhou, Jiakun Zhang, Kyle Newman, Dianna Johnson, Rachel Brennan, Michael A. Dyer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2af30f8f756c41dbaef2dbee86175079
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Descripción
Sumario:	Retinoblastoma is a heritable pediatric cancer driven by mutations in RB1. Here, the authors demonstrate the first patient derived model of retinoblastoma using iPSCs from patients with germline mutations in RB1.