Ex vivo dendritic cell-based (DC) vaccine pulsed with a low dose of liposomal antigen and CpG-ODN improved PD-1 blockade immunotherapy
Abstract Lack of pre-existing tumor infiltrated T cells resulting in resistance to programmed cell death protein 1 (PD-1) blockade therapies can be solved by combining with anti-cancer vaccines and CpG-ODN in increasing T cell expansion and infiltration. Therefore, we prepared an ex vivo dendritic c...
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Autores principales: | Mona Yazdani, Zahra Gholizadeh, Amin Reza Nikpoor, Nema Mohamadian Roshan, Mahmoud Reza Jaafari, Ali Badiee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/2af50bb7f73544da8892e80e7cefb5f6 |
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