Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses

Objectives Fibro-osseous lesions of the paranasal sinuses can present various clinical manifestations. This study aimed to report the long-term clinical course of benign fibro-osseous lesions (BFOLs) in the paranasal sinuses, including clinical and radiologic features. Methods Radiologically confirm...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jung Joo Lee, Gwanghui Ryu, Kyung Eun Lee, Sang Duk Hong, Yong Gi Jung, Hyo Yeol Kim, Hun-Jong Dhong, Seung-Kyu Chung
Formato:	article
Lenguaje:	EN
Publicado:	Korean Society of Otorhinolaryngology-Head and Neck Surgery 2021
Materias:	fibro-osseous lesion paranasal sinus fibrous dysplasia ossifying fibroma Medicine R Otorhinolaryngology RF1-547
Acceso en línea:	https://doaj.org/article/2b010c971ccb4a8591ac8a8a899c1ea1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2b010c971ccb4a8591ac8a8a899c1ea1
record_format	dspace
spelling	oai:doaj.org-article:2b010c971ccb4a8591ac8a8a899c1ea12021-11-18T02:29:22ZLong-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses1976-87102005-072010.21053/ceo.2020.01522https://doaj.org/article/2b010c971ccb4a8591ac8a8a899c1ea12021-11-01T00:00:00Zhttp://www.e-ceo.org/upload/pdf/ceo-2020-01522.pdfhttps://doaj.org/toc/1976-8710https://doaj.org/toc/2005-0720Objectives Fibro-osseous lesions of the paranasal sinuses can present various clinical manifestations. This study aimed to report the long-term clinical course of benign fibro-osseous lesions (BFOLs) in the paranasal sinuses, including clinical and radiologic features. Methods Radiologically confirmed BFOLs between 1994 and 2016, with the exclusion of osteoma cases, were retrospectively reviewed. We compared demographic characteristics between the surgery and observation groups. The reasons for the imaging study, radiographic features, histopathology, and clinical course based on serial image scans were analyzed. Results In total, 183 subjects were selected from a thorough review of head and neck radiologic tests (n=606,068) at a tertiary referral hospital over 22 years. Patients’ mean age was 28.6±18.1 years, and 56.3% were males. A diagnostic imaging workup was performed in 55.7% of patients due to facial asymmetry, headache, skull mass, or other symptoms related to BFOLs. In other patients (37.7%), BFOLs were found incidentally on computed tomography or magnetic resonance imaging. The most common diagnosis was fibrous dysplasia, followed by ossifying fibroma, based on both radiologic exams and histopathologic results. In total, 42.6% of the patients underwent surgery because of subjective symptoms or esthetic concerns. The patients who underwent surgery were younger (P<0.001) and had a longer follow-up duration (P<0.001) than those who underwent observation. Patients who experienced lesion growth (11.5%) were younger (P<0.001) and had more lesion sites (P=0.018) than those who did not, regardless of surgical treatment. Five patients underwent optic nerve decompression, and one patient experienced malignant transformation. Conclusion BFOL in the paranasal sinuses is a rare disease, and most cases were observed without specific treatment. Surgical treatment should be considered in symptomatic patients with aggressive clinical features. Regular observation and management are needed, particularly in younger patients in their teens.Jung Joo LeeGwanghui RyuKyung Eun LeeSang Duk HongYong Gi JungHyo Yeol KimHun-Jong DhongSeung-Kyu ChungKorean Society of Otorhinolaryngology-Head and Neck Surgeryarticlefibro-osseous lesionparanasal sinusfibrous dysplasiaossifying fibromaMedicineROtorhinolaryngologyRF1-547ENClinical and Experimental Otorhinolaryngology, Vol 14, Iss 4, Pp 374-381 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fibro-osseous lesion paranasal sinus fibrous dysplasia ossifying fibroma Medicine R Otorhinolaryngology RF1-547
spellingShingle	fibro-osseous lesion paranasal sinus fibrous dysplasia ossifying fibroma Medicine R Otorhinolaryngology RF1-547 Jung Joo Lee Gwanghui Ryu Kyung Eun Lee Sang Duk Hong Yong Gi Jung Hyo Yeol Kim Hun-Jong Dhong Seung-Kyu Chung Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
description	Objectives Fibro-osseous lesions of the paranasal sinuses can present various clinical manifestations. This study aimed to report the long-term clinical course of benign fibro-osseous lesions (BFOLs) in the paranasal sinuses, including clinical and radiologic features. Methods Radiologically confirmed BFOLs between 1994 and 2016, with the exclusion of osteoma cases, were retrospectively reviewed. We compared demographic characteristics between the surgery and observation groups. The reasons for the imaging study, radiographic features, histopathology, and clinical course based on serial image scans were analyzed. Results In total, 183 subjects were selected from a thorough review of head and neck radiologic tests (n=606,068) at a tertiary referral hospital over 22 years. Patients’ mean age was 28.6±18.1 years, and 56.3% were males. A diagnostic imaging workup was performed in 55.7% of patients due to facial asymmetry, headache, skull mass, or other symptoms related to BFOLs. In other patients (37.7%), BFOLs were found incidentally on computed tomography or magnetic resonance imaging. The most common diagnosis was fibrous dysplasia, followed by ossifying fibroma, based on both radiologic exams and histopathologic results. In total, 42.6% of the patients underwent surgery because of subjective symptoms or esthetic concerns. The patients who underwent surgery were younger (P<0.001) and had a longer follow-up duration (P<0.001) than those who underwent observation. Patients who experienced lesion growth (11.5%) were younger (P<0.001) and had more lesion sites (P=0.018) than those who did not, regardless of surgical treatment. Five patients underwent optic nerve decompression, and one patient experienced malignant transformation. Conclusion BFOL in the paranasal sinuses is a rare disease, and most cases were observed without specific treatment. Surgical treatment should be considered in symptomatic patients with aggressive clinical features. Regular observation and management are needed, particularly in younger patients in their teens.
format	article
author	Jung Joo Lee Gwanghui Ryu Kyung Eun Lee Sang Duk Hong Yong Gi Jung Hyo Yeol Kim Hun-Jong Dhong Seung-Kyu Chung
author_facet	Jung Joo Lee Gwanghui Ryu Kyung Eun Lee Sang Duk Hong Yong Gi Jung Hyo Yeol Kim Hun-Jong Dhong Seung-Kyu Chung
author_sort	Jung Joo Lee
title	Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
title_short	Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
title_full	Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
title_fullStr	Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
title_full_unstemmed	Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses
title_sort	long-term clinical course of benign fibro-osseous lesions in the paranasal sinuses
publisher	Korean Society of Otorhinolaryngology-Head and Neck Surgery
publishDate	2021
url	https://doaj.org/article/2b010c971ccb4a8591ac8a8a899c1ea1
work_keys_str_mv	AT jungjoolee longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT gwanghuiryu longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT kyungeunlee longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT sangdukhong longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT yonggijung longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT hyoyeolkim longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT hunjongdhong longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses AT seungkyuchung longtermclinicalcourseofbenignfibroosseouslesionsintheparanasalsinuses
_version_	1718425151504121856

Long-Term Clinical Course of Benign Fibro-Osseous Lesions in the Paranasal Sinuses

Ejemplares similares