Ub-ProT reveals global length and composition of protein ubiquitylation in cells

Ubiquitylation is a dynamic post-translational modification involved in the regulation of numerous cellular processes. Here the authors describe Ub-ProT: a method to measure the length of substrate-attached ubiquitin chains in biological samples, and demonstrate a critical role for chain length in d...

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Bibliographic Details
Main Authors: Hikaru Tsuchiya, Daocharad Burana, Fumiaki Ohtake, Naoko Arai, Ai Kaiho, Masayuki Komada, Keiji Tanaka, Yasushi Saeki
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/2b014eb25d6c43bab969807300ebe60e
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