Complex DNA knots detected with a nanopore sensor

Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.

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Autores principales: Rajesh Kumar Sharma, Ishita Agrawal, Liang Dai, Patrick S. Doyle, Slaven Garaj
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2b1a76737001404d80ef253081485b51
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spelling oai:doaj.org-article:2b1a76737001404d80ef253081485b512021-12-02T17:32:25ZComplex DNA knots detected with a nanopore sensor10.1038/s41467-019-12358-42041-1723https://doaj.org/article/2b1a76737001404d80ef253081485b512019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12358-4https://doaj.org/toc/2041-1723Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.Rajesh Kumar SharmaIshita AgrawalLiang DaiPatrick S. DoyleSlaven GarajNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rajesh Kumar Sharma
Ishita Agrawal
Liang Dai
Patrick S. Doyle
Slaven Garaj
Complex DNA knots detected with a nanopore sensor
description Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.
format article
author Rajesh Kumar Sharma
Ishita Agrawal
Liang Dai
Patrick S. Doyle
Slaven Garaj
author_facet Rajesh Kumar Sharma
Ishita Agrawal
Liang Dai
Patrick S. Doyle
Slaven Garaj
author_sort Rajesh Kumar Sharma
title Complex DNA knots detected with a nanopore sensor
title_short Complex DNA knots detected with a nanopore sensor
title_full Complex DNA knots detected with a nanopore sensor
title_fullStr Complex DNA knots detected with a nanopore sensor
title_full_unstemmed Complex DNA knots detected with a nanopore sensor
title_sort complex dna knots detected with a nanopore sensor
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2b1a76737001404d80ef253081485b51
work_keys_str_mv AT rajeshkumarsharma complexdnaknotsdetectedwithananoporesensor
AT ishitaagrawal complexdnaknotsdetectedwithananoporesensor
AT liangdai complexdnaknotsdetectedwithananoporesensor
AT patricksdoyle complexdnaknotsdetectedwithananoporesensor
AT slavengaraj complexdnaknotsdetectedwithananoporesensor
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