Complex DNA knots detected with a nanopore sensor
Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.
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Nature Portfolio
2019
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oai:doaj.org-article:2b1a76737001404d80ef253081485b512021-12-02T17:32:25ZComplex DNA knots detected with a nanopore sensor10.1038/s41467-019-12358-42041-1723https://doaj.org/article/2b1a76737001404d80ef253081485b512019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12358-4https://doaj.org/toc/2041-1723Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.Rajesh Kumar SharmaIshita AgrawalLiang DaiPatrick S. DoyleSlaven GarajNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q |
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Science Q Rajesh Kumar Sharma Ishita Agrawal Liang Dai Patrick S. Doyle Slaven Garaj Complex DNA knots detected with a nanopore sensor |
description |
Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states. |
format |
article |
author |
Rajesh Kumar Sharma Ishita Agrawal Liang Dai Patrick S. Doyle Slaven Garaj |
author_facet |
Rajesh Kumar Sharma Ishita Agrawal Liang Dai Patrick S. Doyle Slaven Garaj |
author_sort |
Rajesh Kumar Sharma |
title |
Complex DNA knots detected with a nanopore sensor |
title_short |
Complex DNA knots detected with a nanopore sensor |
title_full |
Complex DNA knots detected with a nanopore sensor |
title_fullStr |
Complex DNA knots detected with a nanopore sensor |
title_full_unstemmed |
Complex DNA knots detected with a nanopore sensor |
title_sort |
complex dna knots detected with a nanopore sensor |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/2b1a76737001404d80ef253081485b51 |
work_keys_str_mv |
AT rajeshkumarsharma complexdnaknotsdetectedwithananoporesensor AT ishitaagrawal complexdnaknotsdetectedwithananoporesensor AT liangdai complexdnaknotsdetectedwithananoporesensor AT patricksdoyle complexdnaknotsdetectedwithananoporesensor AT slavengaraj complexdnaknotsdetectedwithananoporesensor |
_version_ |
1718380296688107520 |