Signalome-wide assessment of host cell response to hepatitis C virus

Development of antiviral strategies depends on an understanding of virus–host interactions. Here, using HCV, Haqshenaset al. show that antibody microarray combined with a targeted siRNA screen can be a powerful tool to identify cellular signalling pathways that are important for virus replication.

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Autores principales:	Gholamreza Haqshenas, Jianmin Wu, Kaylene J. Simpson, Roger J. Daly, Hans J. Netter, Thomas F. Baumert, Christian Doerig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b1ab52c86cf420faa917a8f8b0408df
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spelling	oai:doaj.org-article:2b1ab52c86cf420faa917a8f8b0408df2021-12-02T14:42:33ZSignalome-wide assessment of host cell response to hepatitis C virus10.1038/ncomms151582041-1723https://doaj.org/article/2b1ab52c86cf420faa917a8f8b0408df2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15158https://doaj.org/toc/2041-1723Development of antiviral strategies depends on an understanding of virus–host interactions. Here, using HCV, Haqshenaset al. show that antibody microarray combined with a targeted siRNA screen can be a powerful tool to identify cellular signalling pathways that are important for virus replication.Gholamreza HaqshenasJianmin WuKaylene J. SimpsonRoger J. DalyHans J. NetterThomas F. BaumertChristian DoerigNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gholamreza Haqshenas Jianmin Wu Kaylene J. Simpson Roger J. Daly Hans J. Netter Thomas F. Baumert Christian Doerig Signalome-wide assessment of host cell response to hepatitis C virus
description	Development of antiviral strategies depends on an understanding of virus–host interactions. Here, using HCV, Haqshenaset al. show that antibody microarray combined with a targeted siRNA screen can be a powerful tool to identify cellular signalling pathways that are important for virus replication.
format	article
author	Gholamreza Haqshenas Jianmin Wu Kaylene J. Simpson Roger J. Daly Hans J. Netter Thomas F. Baumert Christian Doerig
author_facet	Gholamreza Haqshenas Jianmin Wu Kaylene J. Simpson Roger J. Daly Hans J. Netter Thomas F. Baumert Christian Doerig
author_sort	Gholamreza Haqshenas
title	Signalome-wide assessment of host cell response to hepatitis C virus
title_short	Signalome-wide assessment of host cell response to hepatitis C virus
title_full	Signalome-wide assessment of host cell response to hepatitis C virus
title_fullStr	Signalome-wide assessment of host cell response to hepatitis C virus
title_full_unstemmed	Signalome-wide assessment of host cell response to hepatitis C virus
title_sort	signalome-wide assessment of host cell response to hepatitis c virus
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2b1ab52c86cf420faa917a8f8b0408df
work_keys_str_mv	AT gholamrezahaqshenas signalomewideassessmentofhostcellresponsetohepatitiscvirus AT jianminwu signalomewideassessmentofhostcellresponsetohepatitiscvirus AT kaylenejsimpson signalomewideassessmentofhostcellresponsetohepatitiscvirus AT rogerjdaly signalomewideassessmentofhostcellresponsetohepatitiscvirus AT hansjnetter signalomewideassessmentofhostcellresponsetohepatitiscvirus AT thomasfbaumert signalomewideassessmentofhostcellresponsetohepatitiscvirus AT christiandoerig signalomewideassessmentofhostcellresponsetohepatitiscvirus
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Signalome-wide assessment of host cell response to hepatitis C virus

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