Insights for Stratification of Risk in Brugada Syndrome

Brugada syndrome (BrS) is an inherited disease with an increased risk of sudden cardiac death (SCD). However, testing identifies genetic disorders in only 20–30% of patients analysed, indicating a gap in knowledge of its genetic aetiology. Diagnosis relies on ECG, and risk stratification in BrS pati...

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Autores principales:	Daniel García Iglesias, José Rubín, Diego Pérez, César Morís, David Calvo
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/2b1eb1f2f459426889a4d69d8f443822
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spelling	oai:doaj.org-article:2b1eb1f2f459426889a4d69d8f4438222021-12-04T16:01:20ZInsights for Stratification of Risk in Brugada Syndrome10.15420/ecr.2018.31.21758-37641758-3756https://doaj.org/article/2b1eb1f2f459426889a4d69d8f4438222019-01-01T00:00:00Zhttps://www.ecrjournal.com/articles/insights-stratification-risk-brugada-syndromehttps://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Brugada syndrome (BrS) is an inherited disease with an increased risk of sudden cardiac death (SCD). However, testing identifies genetic disorders in only 20–30% of patients analysed, indicating a gap in knowledge of its genetic aetiology. Diagnosis relies on ECG, and risk stratification in BrS patients is challenging, primarily because of the complexity of the issue. As a result, clinicians fail to provide the appropriate strategy for SCD prevention for many patients. Several variables and interventions are being studied to improve diagnostics and maximise patient protection. In addition, the scientific community must increase efforts to provide patient care according to knowledge and research for improving stratification of risk. In this article, the authors summarise contemporary evidence on clinical variables and provide an overview of future directions in risk stratification and SCD prevention.Daniel García IglesiasJosé RubínDiego PérezCésar MorísDavid CalvoRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 14, Iss 1, Pp 45-49 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Daniel García Iglesias José Rubín Diego Pérez César Morís David Calvo Insights for Stratification of Risk in Brugada Syndrome
description	Brugada syndrome (BrS) is an inherited disease with an increased risk of sudden cardiac death (SCD). However, testing identifies genetic disorders in only 20–30% of patients analysed, indicating a gap in knowledge of its genetic aetiology. Diagnosis relies on ECG, and risk stratification in BrS patients is challenging, primarily because of the complexity of the issue. As a result, clinicians fail to provide the appropriate strategy for SCD prevention for many patients. Several variables and interventions are being studied to improve diagnostics and maximise patient protection. In addition, the scientific community must increase efforts to provide patient care according to knowledge and research for improving stratification of risk. In this article, the authors summarise contemporary evidence on clinical variables and provide an overview of future directions in risk stratification and SCD prevention.
format	article
author	Daniel García Iglesias José Rubín Diego Pérez César Morís David Calvo
author_facet	Daniel García Iglesias José Rubín Diego Pérez César Morís David Calvo
author_sort	Daniel García Iglesias
title	Insights for Stratification of Risk in Brugada Syndrome
title_short	Insights for Stratification of Risk in Brugada Syndrome
title_full	Insights for Stratification of Risk in Brugada Syndrome
title_fullStr	Insights for Stratification of Risk in Brugada Syndrome
title_full_unstemmed	Insights for Stratification of Risk in Brugada Syndrome
title_sort	insights for stratification of risk in brugada syndrome
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/2b1eb1f2f459426889a4d69d8f443822
work_keys_str_mv	AT danielgarciaiglesias insightsforstratificationofriskinbrugadasyndrome AT joserubin insightsforstratificationofriskinbrugadasyndrome AT diegoperez insightsforstratificationofriskinbrugadasyndrome AT cesarmoris insightsforstratificationofriskinbrugadasyndrome AT davidcalvo insightsforstratificationofriskinbrugadasyndrome
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Insights for Stratification of Risk in Brugada Syndrome

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