C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.

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Autores principales:	Roberta Bulla, Claudio Tripodo, Damiano Rami, Guang Sheng Ling, Chiara Agostinis, Carla Guarnotta, Sonia Zorzet, Paolo Durigutto, Marina Botto, Francesco Tedesco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b1fca59ed134efe8e0682260b30cecc
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spelling	oai:doaj.org-article:2b1fca59ed134efe8e0682260b30cecc2021-12-02T17:32:36ZC1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation10.1038/ncomms103462041-1723https://doaj.org/article/2b1fca59ed134efe8e0682260b30cecc2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10346https://doaj.org/toc/2041-1723C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.Roberta BullaClaudio TripodoDamiano RamiGuang Sheng LingChiara AgostinisCarla GuarnottaSonia ZorzetPaolo DuriguttoMarina BottoFrancesco TedescoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Roberta Bulla Claudio Tripodo Damiano Rami Guang Sheng Ling Chiara Agostinis Carla Guarnotta Sonia Zorzet Paolo Durigutto Marina Botto Francesco Tedesco C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
description	C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.
format	article
author	Roberta Bulla Claudio Tripodo Damiano Rami Guang Sheng Ling Chiara Agostinis Carla Guarnotta Sonia Zorzet Paolo Durigutto Marina Botto Francesco Tedesco
author_facet	Roberta Bulla Claudio Tripodo Damiano Rami Guang Sheng Ling Chiara Agostinis Carla Guarnotta Sonia Zorzet Paolo Durigutto Marina Botto Francesco Tedesco
author_sort	Roberta Bulla
title	C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
title_short	C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
title_full	C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
title_fullStr	C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
title_full_unstemmed	C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
title_sort	c1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2b1fca59ed134efe8e0682260b30cecc
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C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

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