C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system.

Guardado en:

Detalles Bibliográficos
Autores principales:	Tsukasa Kouno, Jonathan Moody, Andrew Tae-Jun Kwon, Youtaro Shibayama, Sachi Kato, Yi Huang, Michael Böttcher, Efthymios Motakis, Mickaël Mendez, Jessica Severin, Joachim Luginbühl, Imad Abugessaisa, Akira Hasegawa, Satoshi Takizawa, Takahiro Arakawa, Masaaki Furuno, Naveen Ramalingam, Jay West, Harukazu Suzuki, Takeya Kasukawa, Timo Lassmann, Chung-Chau Hon, Erik Arner, Piero Carninci, Charles Plessy, Jay W. Shin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b223db146cd404e9768769b7c47b35c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2b223db146cd404e9768769b7c47b35c
record_format	dspace
spelling	oai:doaj.org-article:2b223db146cd404e9768769b7c47b35c2021-12-02T17:31:53ZC1 CAGE detects transcription start sites and enhancer activity at single-cell resolution10.1038/s41467-018-08126-52041-1723https://doaj.org/article/2b223db146cd404e9768769b7c47b35c2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08126-5https://doaj.org/toc/2041-1723Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system.Tsukasa KounoJonathan MoodyAndrew Tae-Jun KwonYoutaro ShibayamaSachi KatoYi HuangMichael BöttcherEfthymios MotakisMickaël MendezJessica SeverinJoachim LuginbühlImad AbugessaisaAkira HasegawaSatoshi TakizawaTakahiro ArakawaMasaaki FurunoNaveen RamalingamJay WestHarukazu SuzukiTakeya KasukawaTimo LassmannChung-Chau HonErik ArnerPiero CarninciCharles PlessyJay W. ShinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tsukasa Kouno Jonathan Moody Andrew Tae-Jun Kwon Youtaro Shibayama Sachi Kato Yi Huang Michael Böttcher Efthymios Motakis Mickaël Mendez Jessica Severin Joachim Luginbühl Imad Abugessaisa Akira Hasegawa Satoshi Takizawa Takahiro Arakawa Masaaki Furuno Naveen Ramalingam Jay West Harukazu Suzuki Takeya Kasukawa Timo Lassmann Chung-Chau Hon Erik Arner Piero Carninci Charles Plessy Jay W. Shin C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
description	Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system.
format	article
author	Tsukasa Kouno Jonathan Moody Andrew Tae-Jun Kwon Youtaro Shibayama Sachi Kato Yi Huang Michael Böttcher Efthymios Motakis Mickaël Mendez Jessica Severin Joachim Luginbühl Imad Abugessaisa Akira Hasegawa Satoshi Takizawa Takahiro Arakawa Masaaki Furuno Naveen Ramalingam Jay West Harukazu Suzuki Takeya Kasukawa Timo Lassmann Chung-Chau Hon Erik Arner Piero Carninci Charles Plessy Jay W. Shin
author_facet	Tsukasa Kouno Jonathan Moody Andrew Tae-Jun Kwon Youtaro Shibayama Sachi Kato Yi Huang Michael Böttcher Efthymios Motakis Mickaël Mendez Jessica Severin Joachim Luginbühl Imad Abugessaisa Akira Hasegawa Satoshi Takizawa Takahiro Arakawa Masaaki Furuno Naveen Ramalingam Jay West Harukazu Suzuki Takeya Kasukawa Timo Lassmann Chung-Chau Hon Erik Arner Piero Carninci Charles Plessy Jay W. Shin
author_sort	Tsukasa Kouno
title	C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
title_short	C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
title_full	C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
title_fullStr	C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
title_full_unstemmed	C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution
title_sort	c1 cage detects transcription start sites and enhancer activity at single-cell resolution
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2b223db146cd404e9768769b7c47b35c
work_keys_str_mv	AT tsukasakouno c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT jonathanmoody c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT andrewtaejunkwon c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT youtaroshibayama c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT sachikato c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT yihuang c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT michaelbottcher c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT efthymiosmotakis c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT mickaelmendez c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT jessicaseverin c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT joachimluginbuhl c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT imadabugessaisa c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT akirahasegawa c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT satoshitakizawa c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT takahiroarakawa c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT masaakifuruno c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT naveenramalingam c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT jaywest c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT harukazusuzuki c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT takeyakasukawa c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT timolassmann c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT chungchauhon c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT erikarner c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT pierocarninci c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT charlesplessy c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution AT jaywshin c1cagedetectstranscriptionstartsitesandenhanceractivityatsinglecellresolution
_version_	1718380419829727232

C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

Ejemplares similares