Neutrophil stunning by metoprolol reduces infarct size

Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on infarcted heart by targeting neutrophils and alterin...

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Autores principales:	Jaime García-Prieto, Rocío Villena-Gutiérrez, Mónica Gómez, Esther Bernardo, Andrés Pun-García, Inés García-Lunar, Georgiana Crainiciuc, Rodrigo Fernández-Jiménez, Vinatha Sreeramkumar, Rafael Bourio-Martínez, José M García-Ruiz, Alfonso Serrano del Valle, David Sanz-Rosa, Gonzalo Pizarro, Antonio Fernández-Ortiz, Andrés Hidalgo, Valentín Fuster, Borja Ibanez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b22a5e28d73475c92751f453e8cb4e3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:2b22a5e28d73475c92751f453e8cb4e32021-12-02T15:37:05ZNeutrophil stunning by metoprolol reduces infarct size10.1038/ncomms147802041-1723https://doaj.org/article/2b22a5e28d73475c92751f453e8cb4e32017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14780https://doaj.org/toc/2041-1723Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on infarcted heart by targeting neutrophils and altering their function and interaction with platelets.Jaime García-PrietoRocío Villena-GutiérrezMónica GómezEsther BernardoAndrés Pun-GarcíaInés García-LunarGeorgiana CrainiciucRodrigo Fernández-JiménezVinatha SreeramkumarRafael Bourio-MartínezJosé M García-RuizAlfonso Serrano del ValleDavid Sanz-RosaGonzalo PizarroAntonio Fernández-OrtizAndrés HidalgoValentín FusterBorja IbanezNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jaime García-Prieto Rocío Villena-Gutiérrez Mónica Gómez Esther Bernardo Andrés Pun-García Inés García-Lunar Georgiana Crainiciuc Rodrigo Fernández-Jiménez Vinatha Sreeramkumar Rafael Bourio-Martínez José M García-Ruiz Alfonso Serrano del Valle David Sanz-Rosa Gonzalo Pizarro Antonio Fernández-Ortiz Andrés Hidalgo Valentín Fuster Borja Ibanez Neutrophil stunning by metoprolol reduces infarct size
description	Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on infarcted heart by targeting neutrophils and altering their function and interaction with platelets.
format	article
author	Jaime García-Prieto Rocío Villena-Gutiérrez Mónica Gómez Esther Bernardo Andrés Pun-García Inés García-Lunar Georgiana Crainiciuc Rodrigo Fernández-Jiménez Vinatha Sreeramkumar Rafael Bourio-Martínez José M García-Ruiz Alfonso Serrano del Valle David Sanz-Rosa Gonzalo Pizarro Antonio Fernández-Ortiz Andrés Hidalgo Valentín Fuster Borja Ibanez
author_facet	Jaime García-Prieto Rocío Villena-Gutiérrez Mónica Gómez Esther Bernardo Andrés Pun-García Inés García-Lunar Georgiana Crainiciuc Rodrigo Fernández-Jiménez Vinatha Sreeramkumar Rafael Bourio-Martínez José M García-Ruiz Alfonso Serrano del Valle David Sanz-Rosa Gonzalo Pizarro Antonio Fernández-Ortiz Andrés Hidalgo Valentín Fuster Borja Ibanez
author_sort	Jaime García-Prieto
title	Neutrophil stunning by metoprolol reduces infarct size
title_short	Neutrophil stunning by metoprolol reduces infarct size
title_full	Neutrophil stunning by metoprolol reduces infarct size
title_fullStr	Neutrophil stunning by metoprolol reduces infarct size
title_full_unstemmed	Neutrophil stunning by metoprolol reduces infarct size
title_sort	neutrophil stunning by metoprolol reduces infarct size
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2b22a5e28d73475c92751f453e8cb4e3
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Neutrophil stunning by metoprolol reduces infarct size

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