Neutralization of schwann cell-secreted VEGF is protective to in vitro and in vivo experimental diabetic neuropathy.

The pathogenetic role of vascular endothelial growth factor (VEGF) in long-term retinal and kidney complications of diabetes has been demonstrated. Conversely, little is known in diabetic neuropathy. We examined the modulation of VEGF pathway at mRNA and protein level on dorsal root ganglion (DRG) n...

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Auteurs principaux: Michela M Taiana, Raffaella Lombardi, Carla Porretta-Serapiglia, Emilio Ciusani, Norberto Oggioni, Jenny Sassone, Roberto Bianchi, Giuseppe Lauria
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
Q
Accès en ligne:https://doaj.org/article/2b2791f597b54bca9c0693acaa633db5
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