SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT

Over last decade, a substantial progress has been made, with respect to understanding of cancer biology and its interplay with the host immune system. Different immunotherapeutic drugs based on recombinant cytokines and monoclonal antibodies are widely used in cancer therapy, and a large number of e...

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Autores principales:	T. S. Nepomnyashchikh, D. V. Antonets, R. A. Maksyutov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2017
Materias:	cancer immunotherapy oncolytic viruses clinical trials vaccinia virus t lymphocytes dendritic cells chimeric antigen receptor Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/2b2e74cb209d4fa0b24f5f2f85dca31b
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spelling	oai:doaj.org-article:2b2e74cb209d4fa0b24f5f2f85dca31b2021-11-18T08:03:46ZSHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT1563-06252313-741X10.15789/1563-0625-2017-2-127-144https://doaj.org/article/2b2e74cb209d4fa0b24f5f2f85dca31b2017-05-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1217https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XOver last decade, a substantial progress has been made, with respect to understanding of cancer biology and its interplay with the host immune system. Different immunotherapeutic drugs based on recombinant cytokines and monoclonal antibodies are widely used in cancer therapy, and a large number of experimental cancer treatments have been developed, many of which are currently undergoing various stages of clinical trials. Recent endorsement of a recombinant oncolytic herpesvirus T-VEC for the treatment of melanoma was an important step towards a more safe and efficient anticancer therapeutics. In this review, we shall mention only some of the most promising cancer immunotherapy strategies, namely, immune checkpoint inhibitors, cellular therapy and oncolytic viruses.T. S. NepomnyashchikhD. V. AntonetsR. A. MaksyutovSPb RAACIarticlecancerimmunotherapyoncolytic virusesclinical trialsvaccinia virust lymphocytesdendritic cellschimeric antigen receptorImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 19, Iss 2, Pp 127-144 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	cancer immunotherapy oncolytic viruses clinical trials vaccinia virus t lymphocytes dendritic cells chimeric antigen receptor Immunologic diseases. Allergy RC581-607
spellingShingle	cancer immunotherapy oncolytic viruses clinical trials vaccinia virus t lymphocytes dendritic cells chimeric antigen receptor Immunologic diseases. Allergy RC581-607 T. S. Nepomnyashchikh D. V. Antonets R. A. Maksyutov SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
description	Over last decade, a substantial progress has been made, with respect to understanding of cancer biology and its interplay with the host immune system. Different immunotherapeutic drugs based on recombinant cytokines and monoclonal antibodies are widely used in cancer therapy, and a large number of experimental cancer treatments have been developed, many of which are currently undergoing various stages of clinical trials. Recent endorsement of a recombinant oncolytic herpesvirus T-VEC for the treatment of melanoma was an important step towards a more safe and efficient anticancer therapeutics. In this review, we shall mention only some of the most promising cancer immunotherapy strategies, namely, immune checkpoint inhibitors, cellular therapy and oncolytic viruses.
format	article
author	T. S. Nepomnyashchikh D. V. Antonets R. A. Maksyutov
author_facet	T. S. Nepomnyashchikh D. V. Antonets R. A. Maksyutov
author_sort	T. S. Nepomnyashchikh
title	SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
title_short	SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
title_full	SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
title_fullStr	SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
title_full_unstemmed	SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
title_sort	short overview of clinical trials with current immunotherapeutic tools for cancer treatment
publisher	SPb RAACI
publishDate	2017
url	https://doaj.org/article/2b2e74cb209d4fa0b24f5f2f85dca31b
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_version_	1718422405975638016

SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT

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