Exendin-4 reduces food intake via the PI3K/AKT signaling pathway in the hypothalamus

Exendin-4 reduces food intake via the PI3K/AKT signaling pathway in the hypothalamus

Abstract Exendin-4 (EX-4), a glucagon-like peptide-1 (GLP-1) receptor agonist, has been shown to reduce food intake and to increase proopiomelanocortin (POMC) gene expression in the hypothalamus. In this study, we examined the potential neural mechanisms by which these effects occur. Male Sprague Da...

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Autores principales: Yan Yang, Pique P. Choi, Wanli W. Smith, Weijie Xu, Delin Ma, Zachary A. Cordner, Nu-Chu Liang, Timothy H. Moran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2b30cf5ad9e742a785d581812b760db1
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