Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naïve and memory T-cell subsets.

Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naïve and memory T-cell subsets.

<h4>Background</h4>Although effective antiretroviral therapy(ART) increases CD4+ T-cell count, responses to ART vary considerably and only a minority of patients normalise their CD4+/CD8+ ratio. Although retention of naïve CD4+ T-cells is thought to predict better immune responses, relat...

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Autores principales: Willard Tinago, Elizabeth Coghlan, Alan Macken, Julie McAndrews, Brenda Doak, Charlotte Prior-Fuller, John S Lambert, Gerard J Sheehan, Patrick W G Mallon, Mater Immunology Study Group
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2b3a9f11019741c5a3af13e0927821b0
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