Dendrite-targeting interneurons control synaptic NMDA-receptor activation via nonlinear α5-GABAA receptors
Somatostatin+ (SOM+ ) GABAergic interneurons are known to fine-tune synaptic plasticity as they inhibit dendritic spikes and burst firing. Here, the authors show that both SOM+ and NOS+ interneurons preferentially recruit nonlinear outward-rectifying GABA(A)R with alpha5 subunit, and that this inhib...
Guardado en:
Autores principales: | Jan M. Schulz, Frederic Knoflach, Maria-Clemencia Hernandez, Josef Bischofberger |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2b44f2781de8400fa51141e60c25aa5b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABAA receptors
por: Xin Zhou, et al.
Publicado: (2020) -
Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission
por: Jin Ye, et al.
Publicado: (2021) -
Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors
por: William T. Ralvenius, et al.
Publicado: (2018) -
Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients
por: Julie Jézéquel, et al.
Publicado: (2017) -
Characterization of zebrafish GABAA receptor subunits
por: Kenichiro Sadamitsu, et al.
Publicado: (2021)