Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.
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Nature Portfolio
2016
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oai:doaj.org-article:2b4b0e9f9cbe44d0921cbc4be51f84a42021-12-02T14:39:48ZUnconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection10.1038/ncomms111912041-1723https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a42016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11191https://doaj.org/toc/2041-1723The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.Lamba Omar SangaréTchilabalo Dilezitoko AlayiBenoit WestermannAgnes HovasseFabien SindikubwaboIsabelle CallebautElisabeth WerkmeisterFrank LafontChristian SlomiannyMohamed-Ali HakimiAlain Van DorsselaerChristine Schaeffer-ReissStanislas TomavoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Lamba Omar Sangaré Tchilabalo Dilezitoko Alayi Benoit Westermann Agnes Hovasse Fabien Sindikubwabo Isabelle Callebaut Elisabeth Werkmeister Frank Lafont Christian Slomianny Mohamed-Ali Hakimi Alain Van Dorsselaer Christine Schaeffer-Reiss Stanislas Tomavo Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
description |
The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen. |
format |
article |
author |
Lamba Omar Sangaré Tchilabalo Dilezitoko Alayi Benoit Westermann Agnes Hovasse Fabien Sindikubwabo Isabelle Callebaut Elisabeth Werkmeister Frank Lafont Christian Slomianny Mohamed-Ali Hakimi Alain Van Dorsselaer Christine Schaeffer-Reiss Stanislas Tomavo |
author_facet |
Lamba Omar Sangaré Tchilabalo Dilezitoko Alayi Benoit Westermann Agnes Hovasse Fabien Sindikubwabo Isabelle Callebaut Elisabeth Werkmeister Frank Lafont Christian Slomianny Mohamed-Ali Hakimi Alain Van Dorsselaer Christine Schaeffer-Reiss Stanislas Tomavo |
author_sort |
Lamba Omar Sangaré |
title |
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
title_short |
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
title_full |
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
title_fullStr |
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
title_full_unstemmed |
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection |
title_sort |
unconventional endosome-like compartment and retromer complex in toxoplasma gondii govern parasite integrity and host infection |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a4 |
work_keys_str_mv |
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