Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.

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Autores principales: Lamba Omar Sangaré, Tchilabalo Dilezitoko Alayi, Benoit Westermann, Agnes Hovasse, Fabien Sindikubwabo, Isabelle Callebaut, Elisabeth Werkmeister, Frank Lafont, Christian Slomianny, Mohamed-Ali Hakimi, Alain Van Dorsselaer, Christine Schaeffer-Reiss, Stanislas Tomavo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a4
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spelling oai:doaj.org-article:2b4b0e9f9cbe44d0921cbc4be51f84a42021-12-02T14:39:48ZUnconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection10.1038/ncomms111912041-1723https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a42016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11191https://doaj.org/toc/2041-1723The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.Lamba Omar SangaréTchilabalo Dilezitoko AlayiBenoit WestermannAgnes HovasseFabien SindikubwaboIsabelle CallebautElisabeth WerkmeisterFrank LafontChristian SlomiannyMohamed-Ali HakimiAlain Van DorsselaerChristine Schaeffer-ReissStanislas TomavoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lamba Omar Sangaré
Tchilabalo Dilezitoko Alayi
Benoit Westermann
Agnes Hovasse
Fabien Sindikubwabo
Isabelle Callebaut
Elisabeth Werkmeister
Frank Lafont
Christian Slomianny
Mohamed-Ali Hakimi
Alain Van Dorsselaer
Christine Schaeffer-Reiss
Stanislas Tomavo
Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
description The retromer complex is a multi-protein component of the endosomal protein sorting machinery. Here, Sangaré et al. identify unique features in the retromer complex of the parasite Toxoplasma gondii, and show that it is crucial for the biogenesis of secretory organelles in this pathogen.
format article
author Lamba Omar Sangaré
Tchilabalo Dilezitoko Alayi
Benoit Westermann
Agnes Hovasse
Fabien Sindikubwabo
Isabelle Callebaut
Elisabeth Werkmeister
Frank Lafont
Christian Slomianny
Mohamed-Ali Hakimi
Alain Van Dorsselaer
Christine Schaeffer-Reiss
Stanislas Tomavo
author_facet Lamba Omar Sangaré
Tchilabalo Dilezitoko Alayi
Benoit Westermann
Agnes Hovasse
Fabien Sindikubwabo
Isabelle Callebaut
Elisabeth Werkmeister
Frank Lafont
Christian Slomianny
Mohamed-Ali Hakimi
Alain Van Dorsselaer
Christine Schaeffer-Reiss
Stanislas Tomavo
author_sort Lamba Omar Sangaré
title Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
title_short Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
title_full Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
title_fullStr Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
title_full_unstemmed Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
title_sort unconventional endosome-like compartment and retromer complex in toxoplasma gondii govern parasite integrity and host infection
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/2b4b0e9f9cbe44d0921cbc4be51f84a4
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