Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

Here, using high spatiotemporal resolution light-sheet and fluorescence microscopy, the authors investigate the role of cytoskeletal components on the intracellular transport of Rab11A and influenza virus (IAV) vRNP), and show a preference for Rab11A movement along microtubules that is not essential...

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Autores principales: Amar R. Bhagwat, Valerie Le Sage, Eric Nturibi, Katarzyna Kulej, Jennifer Jones, Min Guo, Eui Tae Kim, Benjamin A. Garcia, Matthew D. Weitzman, Hari Shroff, Seema S. Lakdawala
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2b51b06a55d942449a18150bc1abcd9c
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Sumario:Here, using high spatiotemporal resolution light-sheet and fluorescence microscopy, the authors investigate the role of cytoskeletal components on the intracellular transport of Rab11A and influenza virus (IAV) vRNP), and show a preference for Rab11A movement along microtubules that is not essential for IAV vRNP transport.