Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association

Here, using high spatiotemporal resolution light-sheet and fluorescence microscopy, the authors investigate the role of cytoskeletal components on the intracellular transport of Rab11A and influenza virus (IAV) vRNP), and show a preference for Rab11A movement along microtubules that is not essential...

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Bibliographic Details
Main Authors: Amar R. Bhagwat, Valerie Le Sage, Eric Nturibi, Katarzyna Kulej, Jennifer Jones, Min Guo, Eui Tae Kim, Benjamin A. Garcia, Matthew D. Weitzman, Hari Shroff, Seema S. Lakdawala
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
Q
Online Access:https://doaj.org/article/2b51b06a55d942449a18150bc1abcd9c
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Summary:Here, using high spatiotemporal resolution light-sheet and fluorescence microscopy, the authors investigate the role of cytoskeletal components on the intracellular transport of Rab11A and influenza virus (IAV) vRNP), and show a preference for Rab11A movement along microtubules that is not essential for IAV vRNP transport.

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