Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence
In regenerative animals, how cells respond to injury signals inducing senescence is unclear. Here, the authors show that cells from highly regenerative mammals are resistant to ROS-induced cellular senescence, but non-regenerating species exhibit mitochondrial dysfunction/senescence in response to h...
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Autores principales: | Sandeep Saxena, Hemendra Vekaria, Patrick G. Sullivan, Ashley W. Seifert |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/2b52ffc90ec046e889e894b5fa15e618 |
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