Olfactory receptor OR2AT4 regulates human hair growth

Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex vivo, suggesting the use of ORT2A4-targeting...

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Autores principales:	Jérémy Chéret, Marta Bertolini, Leslie Ponce, Janin Lehmann, Teresa Tsai, Majid Alam, Hanns Hatt, Ralf Paus
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b5e83cbd8194e4882eb244c8c4f9d63
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spelling	oai:doaj.org-article:2b5e83cbd8194e4882eb244c8c4f9d632021-12-02T17:31:43ZOlfactory receptor OR2AT4 regulates human hair growth10.1038/s41467-018-05973-02041-1723https://doaj.org/article/2b5e83cbd8194e4882eb244c8c4f9d632018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05973-0https://doaj.org/toc/2041-1723Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex vivo, suggesting the use of ORT2A4-targeting odorants as hair growth-promoting agents.Jérémy ChéretMarta BertoliniLeslie PonceJanin LehmannTeresa TsaiMajid AlamHanns HattRalf PausNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jérémy Chéret Marta Bertolini Leslie Ponce Janin Lehmann Teresa Tsai Majid Alam Hanns Hatt Ralf Paus Olfactory receptor OR2AT4 regulates human hair growth
description	Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex vivo, suggesting the use of ORT2A4-targeting odorants as hair growth-promoting agents.
format	article
author	Jérémy Chéret Marta Bertolini Leslie Ponce Janin Lehmann Teresa Tsai Majid Alam Hanns Hatt Ralf Paus
author_facet	Jérémy Chéret Marta Bertolini Leslie Ponce Janin Lehmann Teresa Tsai Majid Alam Hanns Hatt Ralf Paus
author_sort	Jérémy Chéret
title	Olfactory receptor OR2AT4 regulates human hair growth
title_short	Olfactory receptor OR2AT4 regulates human hair growth
title_full	Olfactory receptor OR2AT4 regulates human hair growth
title_fullStr	Olfactory receptor OR2AT4 regulates human hair growth
title_full_unstemmed	Olfactory receptor OR2AT4 regulates human hair growth
title_sort	olfactory receptor or2at4 regulates human hair growth
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2b5e83cbd8194e4882eb244c8c4f9d63
work_keys_str_mv	AT jeremycheret olfactoryreceptoror2at4regulateshumanhairgrowth AT martabertolini olfactoryreceptoror2at4regulateshumanhairgrowth AT leslieponce olfactoryreceptoror2at4regulateshumanhairgrowth AT janinlehmann olfactoryreceptoror2at4regulateshumanhairgrowth AT teresatsai olfactoryreceptoror2at4regulateshumanhairgrowth AT majidalam olfactoryreceptoror2at4regulateshumanhairgrowth AT hannshatt olfactoryreceptoror2at4regulateshumanhairgrowth AT ralfpaus olfactoryreceptoror2at4regulateshumanhairgrowth
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Olfactory receptor OR2AT4 regulates human hair growth

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