Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions

Germ-free mosquitoes generated with current methods exhibit developmental deficits. Here, the authors use genetically modified bacteria to allow complete decolonisation at any developmental stage of Aedes aegypti mosquitoes and show that bacteria support larval development by contributing to folate...

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Autores principales:	Ottavia Romoli, Johan Claes Schönbeck, Siegfried Hapfelmeier, Mathilde Gendrin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b61e9a2b15b4e4e86a332176a400674
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spelling	oai:doaj.org-article:2b61e9a2b15b4e4e86a332176a4006742021-12-02T14:26:44ZProduction of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions10.1038/s41467-021-21195-32041-1723https://doaj.org/article/2b61e9a2b15b4e4e86a332176a4006742021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21195-3https://doaj.org/toc/2041-1723Germ-free mosquitoes generated with current methods exhibit developmental deficits. Here, the authors use genetically modified bacteria to allow complete decolonisation at any developmental stage of Aedes aegypti mosquitoes and show that bacteria support larval development by contributing to folate biosynthesis and enhancing energy storage.Ottavia RomoliJohan Claes SchönbeckSiegfried HapfelmeierMathilde GendrinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ottavia Romoli Johan Claes Schönbeck Siegfried Hapfelmeier Mathilde Gendrin Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
description	Germ-free mosquitoes generated with current methods exhibit developmental deficits. Here, the authors use genetically modified bacteria to allow complete decolonisation at any developmental stage of Aedes aegypti mosquitoes and show that bacteria support larval development by contributing to folate biosynthesis and enhancing energy storage.
format	article
author	Ottavia Romoli Johan Claes Schönbeck Siegfried Hapfelmeier Mathilde Gendrin
author_facet	Ottavia Romoli Johan Claes Schönbeck Siegfried Hapfelmeier Mathilde Gendrin
author_sort	Ottavia Romoli
title	Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
title_short	Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
title_full	Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
title_fullStr	Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
title_full_unstemmed	Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
title_sort	production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2b61e9a2b15b4e4e86a332176a400674
work_keys_str_mv	AT ottaviaromoli productionofgermfreemosquitoesviatransientcolonisationallowsstagespecificinvestigationofhostmicrobiotainteractions AT johanclaesschonbeck productionofgermfreemosquitoesviatransientcolonisationallowsstagespecificinvestigationofhostmicrobiotainteractions AT siegfriedhapfelmeier productionofgermfreemosquitoesviatransientcolonisationallowsstagespecificinvestigationofhostmicrobiotainteractions AT mathildegendrin productionofgermfreemosquitoesviatransientcolonisationallowsstagespecificinvestigationofhostmicrobiotainteractions
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Production of germ-free mosquitoes via transient colonisation allows stage-specific investigation of host–microbiota interactions

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