Artificially cloaked viral nanovaccine for cancer immunotherapy

Artificially cloaked viral nanovaccine for cancer immunotherapy

Cancer therapy using oncolytic virus has shown pre-clinical and clinical efficacy. Here, the authors report ExtraCRAd, an oncolytic virus cloaked with tumour cell membrane and report its therapeutic effects in vitro and in vivo in multiple mouse tumour models.

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Autores principales: Manlio Fusciello, Flavia Fontana, Siri Tähtinen, Cristian Capasso, Sara Feola, Beatriz Martins, Jacopo Chiaro, Karita Peltonen, Leena Ylösmäki, Erkko Ylösmäki, Firas Hamdan, Otto K. Kari, Joseph Ndika, Harri Alenius, Arto Urtti, Jouni T. Hirvonen, Hélder A. Santos, Vincenzo Cerullo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/2b72055f0b5e4f6496735a1c2b068f78
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spelling oai:doaj.org-article:2b72055f0b5e4f6496735a1c2b068f782021-12-02T16:58:05ZArtificially cloaked viral nanovaccine for cancer immunotherapy10.1038/s41467-019-13744-82041-1723https://doaj.org/article/2b72055f0b5e4f6496735a1c2b068f782019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13744-8https://doaj.org/toc/2041-1723Cancer therapy using oncolytic virus has shown pre-clinical and clinical efficacy. Here, the authors report ExtraCRAd, an oncolytic virus cloaked with tumour cell membrane and report its therapeutic effects in vitro and in vivo in multiple mouse tumour models.Manlio FuscielloFlavia FontanaSiri TähtinenCristian CapassoSara FeolaBeatriz MartinsJacopo ChiaroKarita PeltonenLeena YlösmäkiErkko YlösmäkiFiras HamdanOtto K. KariJoseph NdikaHarri AleniusArto UrttiJouni T. HirvonenHélder A. SantosVincenzo CerulloNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Manlio Fusciello
Flavia Fontana
Siri Tähtinen
Cristian Capasso
Sara Feola
Beatriz Martins
Jacopo Chiaro
Karita Peltonen
Leena Ylösmäki
Erkko Ylösmäki
Firas Hamdan
Otto K. Kari
Joseph Ndika
Harri Alenius
Arto Urtti
Jouni T. Hirvonen
Hélder A. Santos
Vincenzo Cerullo
Artificially cloaked viral nanovaccine for cancer immunotherapy
description Cancer therapy using oncolytic virus has shown pre-clinical and clinical efficacy. Here, the authors report ExtraCRAd, an oncolytic virus cloaked with tumour cell membrane and report its therapeutic effects in vitro and in vivo in multiple mouse tumour models.
format article
author Manlio Fusciello
Flavia Fontana
Siri Tähtinen
Cristian Capasso
Sara Feola
Beatriz Martins
Jacopo Chiaro
Karita Peltonen
Leena Ylösmäki
Erkko Ylösmäki
Firas Hamdan
Otto K. Kari
Joseph Ndika
Harri Alenius
Arto Urtti
Jouni T. Hirvonen
Hélder A. Santos
Vincenzo Cerullo
author_facet Manlio Fusciello
Flavia Fontana
Siri Tähtinen
Cristian Capasso
Sara Feola
Beatriz Martins
Jacopo Chiaro
Karita Peltonen
Leena Ylösmäki
Erkko Ylösmäki
Firas Hamdan
Otto K. Kari
Joseph Ndika
Harri Alenius
Arto Urtti
Jouni T. Hirvonen
Hélder A. Santos
Vincenzo Cerullo
author_sort Manlio Fusciello
title Artificially cloaked viral nanovaccine for cancer immunotherapy
title_short Artificially cloaked viral nanovaccine for cancer immunotherapy
title_full Artificially cloaked viral nanovaccine for cancer immunotherapy
title_fullStr Artificially cloaked viral nanovaccine for cancer immunotherapy
title_full_unstemmed Artificially cloaked viral nanovaccine for cancer immunotherapy
title_sort artificially cloaked viral nanovaccine for cancer immunotherapy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2b72055f0b5e4f6496735a1c2b068f78
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