Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon

The assessment of blood glucose levels is necessary for the diagnosis and management of diabetes. The accurate quantification of serum or plasma glucose relies on enzymatic and nonenzymatic methods utilizing electrochemical biosensors. Current research efforts are focused on enhancing the non-invasi...

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Autores principales:	Ahmed Bahgat Radwan, Sreedevi Paramparambath, John-John Cabibihan, Abdulaziz Khalid Al-Ali, Peter Kasak, Rana A. Shakoor, Rayaz A. Malik, Said A. Mansour, Kishor Kumar Sadasivuni
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	sweat sensor glucose detection non-invasive mesoporous carbon bimetallic nanomaterials Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/2b74f0826d324277ac1dcb84afe90953
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spelling	oai:doaj.org-article:2b74f0826d324277ac1dcb84afe909532021-11-25T16:55:46ZSuperior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon10.3390/bios111104632079-6374https://doaj.org/article/2b74f0826d324277ac1dcb84afe909532021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6374/11/11/463https://doaj.org/toc/2079-6374The assessment of blood glucose levels is necessary for the diagnosis and management of diabetes. The accurate quantification of serum or plasma glucose relies on enzymatic and nonenzymatic methods utilizing electrochemical biosensors. Current research efforts are focused on enhancing the non-invasive detection of glucose in sweat with accuracy, high sensitivity, and stability. In this work, nanostructured mesoporous carbon coupled with glucose oxidase (GO<sub>x</sub>) increased the direct electron transfer to the electrode surface. A mixed alloy of CuNi nanoparticle-coated mesoporous carbon (CuNi-MC) was synthesized using a hydrothermal process followed by annealing at 700 °C under the flow of argon gas. The prepared catalyst’s crystal structure and morphology were explored using X-ray diffraction and high-resolution transmission electron microscopy. The electrocatalytic activity of the as-prepared catalyst was investigated using cyclic voltammetry (CV) and amperometry. The findings show an excellent response time of 4 s and linear range detection from 0.005 to 0.45 mM with a high electrode sensitivity of 11.7 ± 0.061 mA mM cm<sup>−2</sup> in a selective medium.Ahmed Bahgat RadwanSreedevi ParamparambathJohn-John CabibihanAbdulaziz Khalid Al-AliPeter KasakRana A. ShakoorRayaz A. MalikSaid A. MansourKishor Kumar SadasivuniMDPI AGarticlesweat sensorglucose detectionnon-invasivemesoporous carbonbimetallic nanomaterialsBiotechnologyTP248.13-248.65ENBiosensors, Vol 11, Iss 463, p 463 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sweat sensor glucose detection non-invasive mesoporous carbon bimetallic nanomaterials Biotechnology TP248.13-248.65
spellingShingle	sweat sensor glucose detection non-invasive mesoporous carbon bimetallic nanomaterials Biotechnology TP248.13-248.65 Ahmed Bahgat Radwan Sreedevi Paramparambath John-John Cabibihan Abdulaziz Khalid Al-Ali Peter Kasak Rana A. Shakoor Rayaz A. Malik Said A. Mansour Kishor Kumar Sadasivuni Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
description	The assessment of blood glucose levels is necessary for the diagnosis and management of diabetes. The accurate quantification of serum or plasma glucose relies on enzymatic and nonenzymatic methods utilizing electrochemical biosensors. Current research efforts are focused on enhancing the non-invasive detection of glucose in sweat with accuracy, high sensitivity, and stability. In this work, nanostructured mesoporous carbon coupled with glucose oxidase (GO<sub>x</sub>) increased the direct electron transfer to the electrode surface. A mixed alloy of CuNi nanoparticle-coated mesoporous carbon (CuNi-MC) was synthesized using a hydrothermal process followed by annealing at 700 °C under the flow of argon gas. The prepared catalyst’s crystal structure and morphology were explored using X-ray diffraction and high-resolution transmission electron microscopy. The electrocatalytic activity of the as-prepared catalyst was investigated using cyclic voltammetry (CV) and amperometry. The findings show an excellent response time of 4 s and linear range detection from 0.005 to 0.45 mM with a high electrode sensitivity of 11.7 ± 0.061 mA mM cm<sup>−2</sup> in a selective medium.
format	article
author	Ahmed Bahgat Radwan Sreedevi Paramparambath John-John Cabibihan Abdulaziz Khalid Al-Ali Peter Kasak Rana A. Shakoor Rayaz A. Malik Said A. Mansour Kishor Kumar Sadasivuni
author_facet	Ahmed Bahgat Radwan Sreedevi Paramparambath John-John Cabibihan Abdulaziz Khalid Al-Ali Peter Kasak Rana A. Shakoor Rayaz A. Malik Said A. Mansour Kishor Kumar Sadasivuni
author_sort	Ahmed Bahgat Radwan
title	Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
title_short	Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
title_full	Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
title_fullStr	Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
title_full_unstemmed	Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon
title_sort	superior non-invasive glucose sensor using bimetallic cuni nanospecies coated mesoporous carbon
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/2b74f0826d324277ac1dcb84afe90953
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Superior Non-Invasive Glucose Sensor Using Bimetallic CuNi Nanospecies Coated Mesoporous Carbon

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