Reaction lumping in metabolic networks for application with thermodynamic metabolic flux analysis

Abstract Thermodynamic metabolic flux analysis (TMFA) can narrow down the space of steady-state flux distributions, but requires knowledge of the standard Gibbs free energy for the modelled reactions. The latter are often not available due to unknown Gibbs free energy change of formation $$, {\Delta...

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Bibliographic Details
Main Authors: Lea Seep, Zahra Razaghi-Moghadam, Zoran Nikoloski
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/2b772b3cdecf41ae9121f43d4a14b07e
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